About Alto Neuroscience, Inc.At Alto Neuroscience, you will play a pivotal role in advancing precision psychiatry and improving how mental health disorders are treated. Join us in building the next generation of personalized neuroscience-based therapeutics.Primary RoleThe Clinical Project Manager is responsible for the end-to-end clinical trial delivery and provides operational oversight of clinical development programs conducted in a hybrid outsourced model. This role ensures high-quality, timely, and compliant execution of clinical studies in accordance with internal SOPs, ICH/GCP guidelines, and regulatory requirements.What you'll doClinical Program & Study OversightProvide operational leadership and oversight for clinical studies from start-up through close-out and reportingEnsure clinical studies are executed in compliance with internal SOPs, ICH/GCP guidelines, and protocol requirementsIdentify study- and program-level risks and develop and implement mitigation strategiesEscalate site, vendor, and study issues appropriately and proactivelyClinical Operations Strategy, Planning & AnalyticsDevelop and own study-level operational plans, including monitoring strategies, vendor oversight plans, communication plans, and risk management plansLead feasibility assessments, site selection strategies, and enrollment planning using data-driven approachesOwn resource forecasting and capacity planning across internal teams and CRO partnersDevelop and manage study budgets, forecasts, and change orders in collaboration with Finance and leadershipApply operational metrics and performance data to continuously optimize study execution and decision-makingSupport program-level operational planning in collaboration with Clinical Operations leadershipCollaborate with internal functional representatives (e.g., Program Physician, Regulatory, Data Management, Medical Writing, Legal, Finance, Quality Assurance, CMC, Clinical Supply) to ensure proper conduct and timely completion of deliverablesClinical Study Documentation & Data CollaborationCoordinate and contribute to the development of clinical study documents, including protocols, Investigator’s Brochures (IBs), informed consent forms (ICFs), case report forms (CRFs), study plans, status reports, and clinical study reportsCollaborate with Data Management to ensure development of CRFs and related plans for appropriate data collection, management, and analysisVendor, Site & Monitoring OversightProvide CRO and vendor oversight, including review and execution of vendor oversight plans and performance metricsAct as the primary operational point of contact for CROs, functional service providers, and other vendorsLead vendor selection, scope definition, governance, and ongoing performance managementEnsure CRO and vendor deliverables meet quality, timeline, and cost expectationsProvide strong oversight of site management and monitoring activities, including CRA performance and workloadParticipate in Site Initiation Visits, co-monitoring visits, audits, and inspections as neededEnsure monitoring strategies are appropriately risk-based and consistently executedPeople LeadershipFoster cross-functional collaboration by guiding, influencing, and supporting team members outside of direct reporting lines to ensure alignment, knowledge sharing, and consistent execution of clinical operations prioritiesManage assigned direct reports and provide oversight of their responsibilities, deliverables, and professional developmentSupport training, mentoring, and performance management of clinical operations staffLocationOnsite- Mountain View, CA*will consider RemoteSalary Range$125,000 - $170,000*depending on qualifications and experience levelQualificationsRequired Skills:BS or BA in Life Sciences or related field (or equivalent experience)Minimum 8+ years of clinical experience in pharmaceutical or biotech environments with increasing levels of responsibility2+ years of clinical project management experienceDemonstrated knowledge of multiple aspects of clinical research operationsData-driven mindset with experience using metrics and analytics to drive decisionsStrong working knowledge of ICH/GCP, ICH E6, and regulatory requirementsProven ability to lead cross-functional teams and manage external vendorsExperience managing and developing direct reports preferredGlobal experience with Phases 2-3 a plusAlto Neuroscience is an equal-opportunity employer that does not discriminate on the basis of sex, age, race, color, religion, marital status, sexual orientation, gender identity, pregnancy, disability, or any other characteristic protected by law. We offer a welcoming and inclusive environment in service to one another, our products, the diverse consumers we represent, and the communities we call home. We do all of this with kindness, empathy and respect for each other. The above is intended to describe the general content of and requirements for the performance of this job. It should not be construed as an exhaustive statement of duties, responsibilities or physical requirements.